Vrtv   3 


(Amendment  3  to  B.  A.  [.  Order  276) 

United  States  Department  of  Agriculture 

BUREAU  OF  ANIMAL  INDUSTRY 


AMENDMENT  3  to  B.  A.  I.   ORDER  276 

Regulations  Governing  the  Preparation,  Sale,  Barter,  Exchange,  Shipment, 
and  Importation  of  Viruses,  Serums,  Toxins,  and  Analogous  Products 
Intended  for  Use  in  the  Treatment  of  Domestic  Animals. 

(Effective  on  and  After  January  1,  1925) 

United  States  Department  of  Acrictilttjre. 

Office  of  the  Secretary, 
Washington,  D.  <?.,  Xovember  29,  1924. 

Under  authority  conferred  by  law  upon  the  Secretary  of  Agri- 
culture, B.  A.  I.  Order  276.  dated  August  18,  1922.  and  effective 
November  1.  1922.  as  amended,  is  hereby  further  amended  in  the 
following  particulars: 

Paragraph  7.  section  1,  and  paragraph  2.  section  3.  Regulation  18. 
and  paragraph  2,  section  5,  Regulation  19.  are  modified  so  as  to 
provide  that  whenever  the  third  day  for  observation  of  test  pigs 
and  of  simultaneous  virus  pigs  falls  on  Sunday  or  on  a  holiday  such 
observation  shall  be  made  on  the  fourth  day  instead  of  the  third  day. 

Paragraph  1.  section  3.  Regulation  18.  is  modified  so  as  to  provide 
a  maximum  weight  for  pigs  of  110  pounds. 

Paragraphs  7  and  8.  section  3.  Regulation  18.  are  revoked. 

Paragraphs  4  and  10.  section  4.  Regulation  18,  are  revoked  and  in 
lieu  thereof  the  following  paragraphs  are  prescribed: 

Paragraph  4- — Simultaneous  virus  which  has  been  mixed  and 
phenolized,  as  provided  in  this  section,  together  with  the  virus- 
stock  sample  and  the  unused  residue  of  the  virus-test  sample. 
shall  be  placed  under  bureau  lock  and  held  as  provided  under 
subdivision  (&).  section  1.  of  Regulation  7  until  such  time  as 
required  test  has  shown  the  batch  of  virus  to  be  free  from 
contamination. 

Paragraph  10. — If  the  animals  which  are  treated  with  hog- 
cholera  virus  as  prescribed  in  the  preceding  paragraph  of  this 
section  do  not  manifest  symptoms  of  any  infectious,  contagious, 
or  communicable  disease  except  as  hereinafter  provided,  the  test 
will  be  declared  "  Satisfactory  for  purity/'  and  the  product  re- 
leased for  marketing.  Should  any  of  the  animals  in  the  test 
succumb  or  should  more  than  one  develop  hog  cholera,  another 
test  should  be  made  as  in  the  first  instance,  except  that  not  less 
than  15  cubic  centimeters  of  the  virus  should  be  used  for  the 
inoculation  of  each  animal  if  the  virus  contains  preservative. 

22045—24 


UNIVERSITY  OF  FLORIDA 


3  1262  08859  2968 


Paragraph  1.  section  :',.  Regulation  19,  is  modified  so  as  to  increase 
to  200,000  the  maximum  number  of  cubic  centimeters  in  which 
batches  of  anti-hog-cholera  serum  prior  to  testing  shall  be  collected. 

Paragraph  2,  section  4.  Regulation  19,  is  modified  so  as  to  increase 
to  200,000  cubic  centimeters  the  amount  of  each  batch  of  anti-hog- 
cholera  serum  for  which  the  establishment  shall  furnish  the  pigs 
specified  in  said  paragraph. 

Paragraph  -k  section  10.  Regulation  ID.  is  revoked  and  in  lieu 
thereof  the  following  paragraph  is  prescribed: 

Paragraph  4.— Should  the  tests  required  by  this  regulation 
be  found  "Satisfactory   for  potency*'  and  "Satisfactory  for 

purity,  as  defined  in  Rules  B  and  E  hereof,  and  the  test  pigs 
receive  doses  of  the  serum  as  prescribed  in  subdivision  (e)\ 
paragraph  2,  of  this  section,  the  product  may  be  marketed  if 
it  is  recommended  for  use  in  doses  not  less  than  those  appear- 
ing in  the  following  table,  except  that  the  product  may  be 
diluted  within  the  provisions  of  subdivision  (a)  of  paragraph 
2  of  this  section  and  marketed  as  provided  for  ••  Unroncent rated 
clear  serum"  under  subdivision  (,/)  of  the  above-named  para- 
graph. This  table  shall  be  a  part  of  trade  labels,  wrappers  and 
the  Jike.  affixed  to  or  used  in  connection  with  each  immediate  or 
true  container  of  the  product: 

Weight  Hinlimim  dose 

Sucking  pigs k;  (i<  c 

Pigs  20  to  40  pounds 04  c    c 

Pigs  40  to  90  pounds -\s  (.'  c' 

Pigs  90  to  120  pounds ;>(;  c[  ,.'" 

Hogs  120  to  150  pounds 44  c,  c 


Hogs  150  to  180  pounds. ... 
Hogs  180  pounds  and  over 


c.    C 


()0    c 


This  amendment,  for  the  purpose  of  identification, 
is  designated  Amendment  3  to  B.  A.  I.  Order  276 
arid  shall  become  and  be  effective  on  and  after  Jan- 
uary 1,  1925. 

Howard  M.  Gore, 
Secretary  of  Agricufyyrt . 


>ML.ST  HUNTING  OKU 


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